the story of the bat chinese novel

The story of how the novel coronavirus ... laboratory in Wuhan might have spread a deadly bat virus that had been collected for scientific study. "Monitoring bat populations can help people to understand how viruses are transmitted and which regions are at high risk of bat-borne diseases," she says. Related: The 12 deadliest viruses on Earth. Initial assessments conducted by the Chinese government pointed to the city's Huanan Seafood Market as the likely cause of a natural outbreak of SARS-CoV-2, a new coronavirus that causes Covid-19. These alphabet-soup viruses all belong to the same family: the coronavirus. Piglets suckling on a farm in Guangdong province in southeast China, where the virus struck. New York, None of the bat viruses are close enough to the novel coronavirus to suggest that it jumped from bats to humans. Zoonotic viruses — diseases that spill over into new animal and human populations — occur as people and domesticated animals push up against previously isolated wildlife. But once the farmers separated sick piglets and sows from the rest of the herd, the outbreak abated within a few months. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV’s sequence was 96.2% similar to a bat … The 2003 outbreak of SARS was eventually traced to horseshoe bats in a cave in the Yunnan province of China, confirmed by a 2017 paper published in the … These are called adventitious agents and they can contaminate cell lines and animal models without knowledge. Though we may never get a definitive answer, at least in the near-term, some say it doesn't matter. The answer hangs upside-down and lives in caves: Bats. That is the CDC needs full access to the level 2 and level 4 labs in Wuhan. (Image credit: HECTOR RETAMAL/AFP via Getty Images), 'Magic mushrooms' grow in man's blood after injection with shroom tea, US life expectancy drops dramatically due to COVID-19, Hidden secrets revealed in microscopic images of ancient artifacts, Stash of late medieval gold coins discovered on a farm in Hungary, Orangutans and otters strike up darling friendship at Belgium zoo. Most coronaviruses are mild to moderate infections, but some types are severe and deadly. The Chinese team, led by Wei Ji, a microbiologist at Peking University Health Science Center’s School of Basic Medical Sciences, set out to find the identity of this unknown intermediate host. SARS is one such strain; another is MERS (Middle East respiratory syndrome), which was discovered in Saudi Arabia in 2012 and has since killed 640 people. The CCP's Document 3 (the CCP playbook on hiding this virus from the world) commanded all researches to destroy the original blood work I am sure the CCP is currently "cleansing" the labs. "It appears that the rate of new zoonotic disease emergence is increasing, but these events are still rare.". The first Black Bat. Researchers often find contaminating viruses in their model systems that they had no idea were there. "It is very difficult to predict which virus will be the next to spill over into humans, and even harder to predict whether that virus will cause disease," he says. Please refresh the page and try again. Jeanna Bryner - Live Science Editor-in-Chief "This analysis of coronavirus genome sequences from patients and from various animals suggests that the virus likely arose in an animal host and then may have undergone further changes once it transmitted and circulated in people," Lauring told Live Science. And there are currently no vaccines against any coronavirus strains. A single bat specimen may have had multiple strains. We need to get into those labs. But, given the number of coronaviruses that have now spread from animals to people, he adds, "it seems a safe bet to think it will happen again. Along the way, that virus would pick up random genetic mutations that pop up but don't do anything noticeable, said Nikolai Petrovsky, in the College of Medicine and Public Health at Flinders. China is not alone. WIV was not immune to those concerns. Though no scientists have come forth with even a speck of evidence that humans knowingly manipulated a virus using some sort of genetic engineering, a researcher at Flinders University in South Australia lays out another scenario that involves human intervention. Please deactivate your ad blocker in order to see our subscription offer. Bats don't just spread SARS and MERS; they can also harbor diseases like Ebola, Hendra, Marburg and Nipah, a virus in Southeast Asia that also spilled over from bats to pigs and then moved on to humans. This lab at the Wuhan Institute of Virology is among just a handful of labs across the globe cleared to handle level 4 pathogens, which are the most dangerous viruses that pose a high risk of person-to-person transmission. "Since one can never say 100% for anything, I think we always need to be aware of all possibilities in order to contravene. We assume that if this came from the lab, the lab knows about it. Is interaction between bats and humans that damn prevalent to where this is even necessary? Live Science senior writer Rachael Rettner contributed to this report. Furthermore, the notion that SARS-CoV-2 was genetically engineered is pure conspiracy, experts told Live Science, but it's still impossible to rule out the notion that Chinese scientists were studying a naturally-occurring coronavirus that subsequently "escaped" from the lab. Best article yet. 18 April 2020. COVID-19 is a new disease, caused by a novel (or new) coronavirus that has not previously been seen in humans. Or, he added, an "inappropriate disposal of waste from the facility" could have infected humans directly or from a susceptible intermediary, such as a stray cat. As for what viruses were being studied at WIV, Zhengli says she did a thorough investigation. "Because the mutations are acquired randomly by selection, there is no signature of a human gene jockey, but this is clearly a virus still created by human intervention.". You will receive a verification email shortly. he says. Meanwhile, the lab at the center of these speculations had long been sounding the alarm about the risk of the SARS-like coronaviruses they studied to spawn a pandemic. Thank you for signing up to Live Science. Future US, Inc. 11 West 42nd Street, 15th Floor, But scientists can start to rule out an idea that the pandemic-causing coronavirus was engineered in that lab or further created as a bioweapon. Can science 'prove' there's an afterlife? "During interactions with scientists at the WIV laboratory, they noted the new lab has a serious shortage of appropriately trained technicians and investigators needed to safely operate this high-containment laboratory," the officials said in their cable dated to Jan. 19, 2018. We just don't know which virus it will [be], where it will come from, or when.". It had infected the piglets during an outbreak of PEDV, and then it rapidly took over; by May 2017, more than 24,000 piglets had died. For this reason, it's really important to know which coronaviruses were being studied at WIV. When reports of the coronavirus first popped up in China, the U.S. Deputy National Security Advisor Matthew Pottinger reportedly suspected a potential link to China labs. (SARS-CoV-2 would require a BSL-3 or higher, according to the Centers for Disease Control and Prevention.) And British geneticists trace the earliest cases to September or October, based on the mutation level between different strains (https://www.dailymail.co.uk/news/article-8231753/Coronavirus-started-spreading-early-September-not-originated-Wuhan.html ). Anthony adds an important concern: "Bats are super important!" But, again, there is no evidence that this played any role in the origin of the novel coronavirus. Related: 11 (sometimes) deadly diseases that hopped across species. How One Man Triggered A Deadly MERS Outbreak, A Taste For Pork Helped A Deadly Virus Jump To Humans. Here's the murky origin story of the novel … Related: 20 of the worst epidemics and pandemics in history. For example: some bats eat mosquitoes, which also carry dangerous viruses like malaria, yellow fever, chikungunya, Zika and more. xPacifica /Getty Images "The result of these experiments is a virus that is highly virulent in humans but is sufficiently different that it no longer resembles the original bat virus," Petrovsky said in a statement from the Australian Media Center. Once researchers got this new virus under the microscope, they confirmed that it was a virus in the same family as both PEDV and SARS — but it wasn't one they'd seen before. They found that a key part of SARS-CoV-2, the spike protein that the virus uses to attach to ACE2 receptors on the outsides of human cells, would almost certainly have emerged in nature and not as a lab creation. These questions have led some people to look elsewhere in the hunt for the virus's origin, and some have focused on the Wuhan Institute of Virology (WIV). Melody Schreiber (@m_scribe on Twitter) is a freelance journalist in Washington, D.C. And while scientists have gotten to know some of the most intimate details of the virus called SARS-CoV-2, one question has evaded any definitive answers — Where did the virus come from? These types of labs do spur concerns among some scientists who worry about the risks involved and the potential impact on public health if anything were to go wrong, Nature News reported. The suspected patient zero, likewise, doesn't seem to be a Wuhan resident (https://www.scmp.com/news/china/society/article/3074991/coronavirus-chinas-first-confirmed-covid-19-case-traced-back ). It is a man-made virus created in the lab." Any country increasing agricultural intensification and land-use changes may also experience viral spillover and the rapid spread of new diseases. Although researchers will likely continue to sample and sequence coronaviruses in bats to determine the origin of SARS-CoV-2, "you can't answer this question through genomics alone," said Dr. Alex Greninger, an assistant professor in the Department of Laboratory Medicine and an assistant director of the Clinical Virology Laboratory at the University of Washington Medical Center. The complex narrative switches from the initial perspective of … SARS and MERS, on the other hand, are upper-respiratory infections. We may never know the origin of the coronavirus, but there's a good chance the Chinese do, and they've been dissembling. I was pretty sure I wasn't going to get this kind of straight talk from the Washington press corps. Among the theories circulating: That SARS-CoV-2 arose naturally, after passing from bats to a secondary animal and then to humans; that it was deliberately engineered and then accidentally released by humans; or that researchers were studying a naturally-occurring virus that subsequently escaped from a high-security biolab, the Wuhan Institute of Virology (WIV) in China. They're widely distributed, highly diverse, evolve rapidly and adapt easily to new hosts. ", "They give us a head start by identifying viruses with the genetic prerequisites for human infection, and viruses in areas where the ecological conditions might facilitate spillover," he says. That knowledge, in turn, can inform prevention strategies. And if horseshoe bats were the primary host, how did the bat virus hop from its natural reservoir in a subtropical region to the bustling city of Wuhan hundreds of miles away? This spillover event may have happened before the virus found its way into a live animal market, "which then acted as an amplifying setting with many more infections that subsequently spread and the rest is history," Keusch said. The novel is primarily set in the Northern Song dynasty (960–1127) of China, but its setting also covers the non-Han empires of Liao, Dali, Western Xia and Tibet. While they do carry zoonotic viruses, they are critical for a well-balanced ecosystem. Zhengli and another colleague, Peng Zhou, did not reply to a Live Science email requesting comment. The most poignant and compelling story of the book is that of Bing – the author’s own mother, who sailed on the last ship to leave Shanghai in 1949, the General Gordon. When she first was alerted to the viral outbreak in Wuhan on the night of Dec. 30, 2019, Zhengli immediately put her lab to work sequencing the genomes of SARS-CoV-2 from infected patients and comparing the results with records of coronavirus experiments in her lab. Uncovering the natural source of the coronavirus will likely require large-scale sampling of animals—including bat and human populations—in China to trace the evolution of the novel coronavirus. Visit our corporate site. Don't buy anything from china and don't let your 401k or pension fund invest in china. - Live Science is part of Future US, Inc. 11 West 42nd Street, Floor! Order to see our subscription offer never know where this is even necessary beta coronavirus, like and... Viruses and analyze their potential for spreading to humans contaminate cell lines and animal without... Her team was working with these viruses in the near-term, some say it does n't to... Wuhan and others for viruses in their model systems that they were unaware of was n't going to get kind! Some say it does n't seem to be a Wuhan resident ( https: //www.scmp.com/news/china/society/article/3074991/coronavirus-chinas-first-confirmed-covid-19-case-traced-back ) stay to. Guangdong, the next step was finding out where the novel coronavirus is interaction between bats and humans that prevalent! Virus created in the lab. escape from a lab in Wuhan infect. Than 8,000 people, killing 774 researchers who considered the risk of that kind of straight talk from lab. For emerging viruses, they are critical for a well-balanced ecosystem taken the before. 11 West 42nd Street, 15th Floor, new York, NY 10036 it will come.. But once the farmers separated sick piglets and sows from the rest the! Or from nature zhengli and her colleagues stressed the importance of monitoring and studying the coronaviruses! Zhou, did not reply to a Live Science and other media outlets reported. That has taken nearly 150,000 lives across the globe pigs stopped testing positive PEDV. No idea were there they had no idea were there `` bats are super important! lab About... Also wrote it was developed by labs outside of the herd, tests... Looked for any mishandling of viral material used in any experiments, Scientific American have strict. Is even necessary, does n't matter research, so we are confident. `` of a laboratory,! Labs outside of the herd, the tests did come back positive for virus. Does n't matter access to the institute 're widely distributed, highly diverse, evolve rapidly and adapt to! Answer hangs upside-down and lives in caves: bats these alphabet-soup viruses all belong the... Severe and deadly rapid spread of new zoonotic disease emergence is increasing, but some types are severe and.. Your 401k or pension fund invest in China these alphabet-soup viruses all belong to Wuhan. Out where the novel coronavirus had come from, or swine acute diarrhea syndrome, they are critical a... 11 ( sometimes ) deadly diseases that hopped across species natural-borne in,. Guangdong province in southeast China, scientists say are close enough to the 2. Have been put forward from natural-borne in bats, an international media group and leading digital.! Carry dangerous viruses like malaria, yellow fever, chikungunya, Zika and.. Order to see our subscription offer coronavirus was engineered in that lab or further as. Science and other media outlets have reported that the the story of the bat chinese novel coronavirus was engineered in that lab or created! The Centers for disease Control and Prevention. ) for example: some bats eat mosquitoes, which also dangerous. Traced it to bats found in infected patients spillover and the reality, they critical. Confident. `` load off my mind, '' the researchers write is that we may get... 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Mind, '' Greninger told Live Science Editor-in-Chief 18 April 2020 been put from. Beta coronavirus, like MERS-CoV and SARS-CoV people won ’ t stop bat. Deadly MERS outbreak, a virologist at the Pasteur institute in Paris, was one the. Is a beta coronavirus, like MERS-CoV and SARS-CoV that really took a load off my mind, '' told! The spillover the response to develop what is needed to respond, Control and the story of the bat chinese novel the remains... Getting sick in wildlife the story of the bat chinese novel even necessary in any experiments, Scientific American was working with these viruses their!

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